408 research outputs found

    Ambient particulate air pollution (PM2.5) is associated with the ratio of type 2 diabetes to obesity

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    JRS was supported by the 1000 talents program and a Wolfson merit award from the Royal Sociey. MM was supported by a TWAS studentship of the Chinese Academy of Sciences.Peer reviewedPublisher PD

    Mice that gorged during dietary restriction increased foraging related behaviors and differed in their macronutrient preference when released from restriction

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    This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited. Funding This work was funded by the University of Aberdeen. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Acknowledgements We are grateful for the assistance provided by Caitlin Begley, the animal house staff at the University of Aberdeen, Paula Redman and Nick Fewkes.Peer reviewedPublisher PD

    Type 2 diabetes, but not obesity, prevalence is positively associated with ambient temperature

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    Acknowledgements This study was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB13030000), the National Science foundation of China (microevolution program NSFC91431102) and the 1000 talents program. We are grateful to members of the Molecular Energetics group in Beijing and the Energetics group in Aberdeen, UK for valuable discussion of the data and analysis. All data analysed in this paper are already available in the public domain.Peer reviewedPublisher PD

    Low resting metabolic rate is associated with greater lifespan because of a confounding effect of body fatness

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    Acknowledgments: This work was funded by the Biotechnology and Biological Sciences Research Council (BBSRC) grant BB/C516228/1 to J.R.S. We thank Jackie Duncan and Sarah Johnston for helping with DNA protocol assays and Lobke Vaanholt for helping with antioxidant enzyme protocols. We are grateful to the staff of the animal house for the care of our animals and to Paula Redman and Peter Thomson who provided technical support for the DLW assays. Open Access: This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.Peer reviewedPublisher PD

    High fat diet causes rebound weight gain

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    Acknowledgements This work was funded by a grant from Action Medical Research (SP4581). We are grateful to the animal house staff for looking after the animals.Peer reviewedPublisher PD

    The '39 steps' : an algorithm for performing statistical analysis of data on energy intake and expenditure

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    This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Share Alike License (http://creativecommons.org/licenses/by-nc-sa/3.0), which permits unrestricted non-commercial use, distribution and reproduction in any medium provided that the original work is properly cited and all further distributions of the work or adaptation are subject to the same Creative Commons License terms.Peer reviewedPublisher PD

    Why lipostatic set point systems are unlikely to evolve

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    My work on body weight regulation has been generously supported by the Chinese Academy of Sciences Xiandao B eGPS project (XDB13030100), the National Science Foundation of China microevolution program (NSFC91431102), the 1000 talents program and a Wolfson merit Professorship from the UK Royal Society.Peer reviewedPublisher PD

    The evolution of body fatness : trading off disease and predation risk

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    Funding My work on body weight regulation has been generously supported by the Chinese Academy of Sciences Xiandao B eGPS project (XDB13030100), the National Natural Science Foundation of China microevolution program (NSFC91431102), the 1000 talents program and a Wolfson merit Professorship from the UK Royal Society.Peer reviewedPublisher PD

    Why does caloric restriction increase life and healthspan? : The 'clean cupboards' hypothesis

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    Funding Information: This work was supported by the National Natural Science Foundation of China (91731303 and 91649108), the Royal Society (Wolfson Merit Award), the Biotechnology and Biological Sciences Research Council of the UK (BB/P009875/1), the KC Wong Education Foundation and the Chinese Academy of Sciences (XDB 13030100).Peer reviewedPublisher PD

    A new journal for a new age

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